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High-risk E6 and E7 bind to p53 and pRb and inactivate their functions with dysregulation of the cell cycle. Genomes and genetics Lecture 3 papilloma vescica femminile Hpv virus genome.

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Interacting human papillomavirus hpv genome various cellular proteins, E6 and E7 influence fundamental cellular functions like cell cycle regulation, telomere maintenance, susceptibility to apoptosis, intercellular adhesion and regulation of immune responses.

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Hpv virus genome. HPV E6 and E7 oncoproteins are the critical molecules in the process of malignant tumour formation.